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Cover Picture : The cover illustrates the finding that cortical neurons respond to fast-varying fluctuating currents (e.g. blue waveform), encoding input modulations into their instantaneous firing rate (spike trains in the background). Mimicking in vivo-like irregular background activity in slice recordings, we studied the dynamics of neuronal response to sinusoidal inputs and found that pyramidal cells relay them without significant attenuation up to 200 Hz, 10 times faster than cells own mean firing rate (i.e. 20 Hz). See Köndgen et al. 2008. The dynamical response properties of neocortical neurons to temporally modulated noisy inputs in vitro. Cereb Cortex 18(9): 2086-2097.

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