Cover Picture: Parvalbumin-expressing basket, bistratified and axo-axonic interneurons in the hippocampus communicate electrically via gap junctions and chemically via GABAA receptors. Middle: Electron micrograph of a gap junction between two interneuron dendrites; horseradish-peroxidase product (black) marks immunoreactivity for connexin36 channels. Right top: Immunogold particles (red) marking connexin36 proteins at a dendro-dendritic gap junction. Below: Immunofluorescence micorgraph showing that connxin36 immunoreactive dots (red) are located between dendritic crossings of parvalbumin-expressing interneuron dendrites (green). Middle bottom: Confocal view of a neurobiotin labelled dendrite of an identified axo-axonic cell (blue) expressing connexin36-immunoreactive dots at the crossing with another interneuron dendrite immuno-positive for the α1 subunit of GABAA receptor (yellow). Left: Confocal micrograph of a neurobiotin labelled dendrite of an identified axo-axonic cell (blue) weakly immuno-positive for the α1 subunit of GABAA receptor (yellow) in comparison to strongly immuno-positive neighbouring inter-neuron dendrites. We thank Mr. Ben Micklem for the assembly of the picture.
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