Cover Picture: The cover illustration is a mosaic of examples from Patricia Goldman-Rakic's work which highlights the importance of persistent activity in the cellular basis of working memory. The background image is that of a pyramidal neuron from the primate prefrontal cortex, as indicated in the schematic of the macaque brain (upper left). Pyramidal and non-pyramidal cells form recurrent microcircuits (lower left), which generate persistent activity during the delay period of working memory tasks (lower right). Such microcircuits are believed to underlie the columnar organization of the primate prefrontal cortex (upper right), and subserve the highest aspects of cerebral cortical function.
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