Skip Navigation



Cerebral Cortex Advance Access published online on August 7, 2006
Cerebral Cortex, doi:10.1093/cercor/bhl043
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
17/6/1323    most recent
bhl043v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Peissig, J. J.
Right arrow Articles by Sheinberg, D. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Peissig, J. J.
Right arrow Articles by Sheinberg, D. L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2006. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Article

Effects of Long-Term Object Familiarity on Event-Related Potentials in the Monkey

Jessie J. Peissig 1, Jedediah Singer 1, Keisuke Kawasaki 1, and David L. Sheinberg 1 *

1 Department of Neuroscience, Brown University, Providence, RI, USA

* To whom correspondence should be addressed.
David L. Sheinberg, E-mail: David_Sheinberg{at}brown.edu


  Abstract

Although some change in the neural representation of an object must occur as it becomes familiar, the nature of this change is not fully understood. In humans, it has been shown that the N170--an evoked visual potential--is enhanced for classes of objects for which people have visual expertise. In this study, we explored whether monkeys show a similar modulation in event-related potential (ERP) amplitude as a result of long-term familiarity by recording ERPs with chronically implanted electrodes over extended training periods spanning many sessions. In each of 3 experiments, we found larger amplitude visual evoked responses to highly familiar images for the time period of 120-250 ms after stimulus onset. This difference was found when the monkeys were trained in an individual-level discrimination task, in a task that required only color discrimination, and even following a viewing-only task. We thus observed this familiarity effect across several tasks and different object categories and further found that the difference between "familiar" and "novel" became smaller as the animals gained experience with the previously unfamiliar objects across multiple test sessions. These data suggest that changes in visual responses associated with familiarity are evident early in the evoked visual response, are robust, and may be automatic, driven at least in part by repeated object exposure.

Keywords: event-related potentials; familiarity; object recognition; primates; vision; visual expertise.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Cereb CortexHome page
A. Akrami, Y. Liu, A. Treves, and B. Jagadeesh
Converging Neuronal Activity in Inferior Temporal Cortex during the Classification of Morphed Stimuli
Cereb Cortex, April 1, 2009; 19(4): 760 - 776.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
Y. Liu, S. O. Murray, and B. Jagadeesh
Time Course and Stimulus Dependence of Repetition-Induced Response Suppression in Inferotemporal Cortex
J Neurophysiol, January 1, 2009; 101(1): 418 - 436.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
Y. Liu and B. Jagadeesh
Neural Selectivity in Anterior Inferotemporal Cortex for Morphed Photographic Images During Behavioral Classification or Fixation
J Neurophysiol, August 1, 2008; 100(2): 966 - 982.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.