Skip Navigation



Cerebral Cortex Advance Access published online on September 21, 2005
Cerebral Cortex, doi:10.1093/cercor/bhj038
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
16/7/960    most recent
bhj038v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Mazzola, L.
Right arrow Articles by Mauguière, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mazzola, L.
Right arrow Articles by Mauguière, F.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2005. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Article

Somatosensory and Pain Responses to Stimulation of the Second Somatosensory Area (SII) in Humans. A Comparison with SI and Insular Responses

L. Mazzola 1, J. Isnard 1, and F. Mauguière 1*

1 Department of Functional Neurology and Epileptology, Federative Institute of Neurosciences, Hôpital Neurologique, Lyon, France

* To whom correspondence should be addressed.
F. Mauguière, E-mail: mauguier{at}univ-lyon1.fr


  Abstract

Somatosensory and pain responses to direct intracerebral stimulations of the SII area were obtained in 14 patients referred for epilepsy surgery. Stimulations were delivered using transopercular electrodes exploring the parietal opercular cortex (SII area), the suprasylvian parietal cortex (SI area) and the insular cortex. SII responses were compared to those from adjacent SI and insular cortex. In the three areas we elicited mostly somatosensory responses, including paresthesiae, temperature and pain sensations. The rate of painful sensations (10%) was similar in SII and in the insula, while no painful sensation was evoked in SI. A few non-somatosensory responses were evoked by SII stimulation. Conversely various types of non-somatosensory responses (auditory, vegetative, vestibular, olfacto-gustatory, etc.) were evoked only by insular stimulation, confirming that SII, like SI, are mostly devoted to the processing of somatosensory inputs whereas the insular cortex is a polymodal area. We also found differences in size and lateralization of skin projection fields of evoked sensations between the three studied areas, showing a spatial resolution of the somatotopic map in SII intermediate between those found in SI and insula. This study shows the existence of three distinct somatosensory maps in the suprasylvian, opercular and insular regions, and separate pain representations in SII and insular cortex.

Keywords: insula; intracerebral stimulation; pain; second somatosensory area; somesthesia.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Neurosci.Home page
R. P. Dum, D. J. Levinthal, and P. L. Strick
The Spinothalamic System Targets Motor and Sensory Areas in the Cerebral Cortex of Monkeys
J. Neurosci., November 11, 2009; 29(45): 14223 - 14235.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
D. S. Rosenberg, F. Mauguiere, H. Catenoix, I. Faillenot, and M. Magnin
Reciprocal Thalamocortical Connectivity of the Medial Pulvinar: A Depth Stimulation and Evoked Potential Study in Human Brain
Cereb Cortex, June 1, 2009; 19(6): 1462 - 1473.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. S. Beauchamp and T. Ro
Neural Substrates of Sound-Touch Synesthesia after a Thalamic Lesion
J. Neurosci., December 10, 2008; 28(50): 13696 - 13702.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. Frot, F. Mauguiere, M. Magnin, and L. Garcia-Larrea
Parallel Processing of Nociceptive A-{delta} Inputs in SII and Midcingulate Cortex in Humans
J. Neurosci., January 23, 2008; 28(4): 944 - 952.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
Y. Oshiro, A. S. Quevedo, J. G. McHaffie, R. A. Kraft, and R. C. Coghill
Brain Mechanisms Supporting Spatial Discrimination of Pain
J. Neurosci., March 28, 2007; 27(13): 3388 - 3394.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
U. Baumgartner, W. Tiede, R.-D. Treede, and A. D. Craig
Laser-Evoked Potentials Are Graded and Somatotopically Organized Anteroposteriorly in the Operculoinsular Cortex of Anesthetized Monkeys
J Neurophysiol, November 1, 2006; 96(5): 2802 - 2808.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.