Cerebral Cortex Advance Access published online on December 22, 2004
Cerebral Cortex, doi:10.1093/cercor/bhi002
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 Laboratory of Sensorimotor Research, National Institutes of Health; Center for Neurobiology and Behavior and Department of Psychiatry, Columbia University
* To whom correspondence should be addressed. The monkey's lateral intraparietal area (LIP) has been associated with attention and saccades. LIP neurons have visual on-responses to objects abruptly appearing in their receptive fields (RFs) and sustained activity preceding saccades to the RF. We studied the relationship between the on-responses and delay activity in LIP using a ‘stable-array’ task. Monkeys viewed eight distinct, continuously illuminated objects, arranged in a circle with at least one object in the RF. A cue flashed instructing the monkey to make a saccade, after a delay, to the stable object physically matching the cue. The location of the cue was fixed in trial blocks, either in or out of the RF. If the cue was outside the RF, neurons developed delay-period activity tuned for the direction of the saccade target at
Article
Simultaneous Representation of Saccade Targets and Visual Onsets in Monkey Lateral Intraparietal Area
2 Laboratory of Sensorimotor Research, National Institutes of Health; MRC-Cognition and Brain Science Unit; Department of Experimental Psychology, Oxford University
Michael E. Goldberg, E-mail: jg2141{at}columbia.edu
Abstract 
190 ms after cue onset. If the cue appeared in the RF, neurons initially responded to cue onset and developed tuning for saccade direction only toward the end of the delay period, 390 ms after cue onset. The cue- and saccade-target responses coexisted throughout a significant portion of the delay period. The results show that visual-on responses and delay-period activity in LIP are functionally separable, and that, although highly selective, the salience representation in LIP can contain more than one object at a time.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  T. Collins, D. Vergilino-Perez, L. Delisle, and K. Dore-Mazars Visual Versus Motor Vector Inversions in the Antisaccade Task: A Behavioral Investigation With Saccadic Adaptation J Neurophysiol, May 1, 2008; 99(5): 2708 - 2718. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Macaluso, C. D. Frith, and J. Driver Delay Activity and Sensory-Motor Translation During Planned Eye or Hand Movements to Visual or Tactile Targets J Neurophysiol, November 1, 2007; 98(5): 3081 - 3094. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. G. Constantin, H. Wang, J. C. Martinez-Trujillo, and J. D. Crawford Frames of Reference for Gaze Saccades Evoked During Stimulation of Lateral Intraparietal Cortex J Neurophysiol, August 1, 2007; 98(2): 696 - 709. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. F Balan and J. Gottlieb Integration of Exogenous Input into a Dynamic Salience Map Revealed by Perturbing Attention J. Neurosci., September 6, 2006; 26(36): 9239 - 9249. [Abstract] [Full Text] [PDF]
|
|