Skip Navigation


Cerebral Cortex Advance Access first published online on May 13, 2004
This version published online on August 5, 2004
Cerebral Cortex, doi:10.1093/cercor/bhh081
© 2004 by Oxford University Press
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
14/11/1207    most recent
bhh081v2
bhh081v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Blanch, R. J.
Right arrow Articles by Hadley, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Blanch, R. J.
Right arrow Articles by Hadley, D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Article

Are There Gender-specific Neural Substrates of Route Learning from Different Perspectives?

Richard J. Blanch 1*, David Brennan 1, Barrie Condon 1, Celestine Santosh 2, Donald Hadley 2

1 Department of Clinical Physics, Institute of Neurological Sciences, Southern General Hospital, Glasgow G51 4TF, UK
2 Department of Neuroradiology, Institute of Neurological Sciences, Southern General Hospital, Glasgow G51 4TF, UK

* To whom correspondence should be addressed. E-mail: rich{at}blanch.org.


  Abstract

Psychological studies have demonstrated sex differences in performance and tactics for route learning. Route information can be encoded in different ways, such as the survey perspective (as in maps) and the route perspective (as we experience the world). Here we show, using functional magnetic resonance imaging, that men and women use the same brain areas to learn routes from both perspectives, and that the observed sex differences in route learning are not due to differences in the parts of the brain being used. We also show that many of the same brain areas are used in route learning from both perspectives, such as the parahippocampus, precuneus, posterior cingulate gyrus and middle frontal gyrus. However, paired comparisons of route learning from both perspectives shows that the survey perspective activates the superior and middle temporal gyri and the angular gyrus, which are not activated in the route perspective.

Keywords: echoplanar imaging, magnetic resonance imaging, memory, psychophysiology, parahippocampal gyrus.
Corrigendum: The author wishes to acknowledge an additional institution. Version 2 contains the additional acknowledgement in the Notes section
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.