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Cerebral Cortex, Vol. 10, No. 3, 205, March 2000
© 2000 Oxford University Press

The Mysterious Orbitofrontal Cortex. Foreword

Carmen Cavada and Wolfram Schultz1

Department of Morphology, Medical School, Autonomous University of Madrid, Spain and , 1 Institute of Physiology, University of Fribourg, Switzerland


   Introduction
 
One of the least explored and least understood regions of the primate cerebral cortex is the orbitofrontal cortex, a part of the frontal lobe that lies on the roof of the orbit. Classic clinical evidence suggests that the orbitofrontal cortex is involved in critical human functions, such as social adjustment and the control of mood, drive and responsibility, traits that are crucial in defining the ‘personality’ of an individual. Phineas Gage is . . . [Full Text of this Article]


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