Cerebral Cortex, Vol. 10, No. 10, 963-973,
October 2000
© 2000 Oxford University Press
Cellular and Molecular Mechanisms of Dendrite Growth
Center for Neuroscience, University of California, Davis, CA 95616, USA
Proper growth and branching of dendrites are crucial for nervous system function; patterns of dendritic arborization determine the nature and amount of innervation that a neuron receives and specific dendritic membrane properties define its computational capabilities. Until recently, there was relatively little known about the cellular and molecular mechanisms of dendritic growth, perhaps because dendrites were historically considered to be intrinsically determined, passive elements in the formation of connections in the nervous system. In the last few years, however, overwhelming evidence has accumulated indicating that dendritic growth is remarkably dynamic and responsive to environmental signals, including guidance molecules and levels and patterns of activity. This manuscript reviews our current understanding of the cellular and molecular mechanisms of dendritic growth, the influence of activity in sculpting specific patterns of dendritic arbors, and a potential integral role for dendrites in activity-dependent development of circuits in the nervous system.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  J. George, S. M. Dravid, A. Prakash, J. Xie, J. Peterson, S. V. Jabba, D. G. Baden, and T. F. Murray Sodium Channel Activation Augments NMDA Receptor Function and Promotes Neurite Outgrowth in Immature Cerebrocortical Neurons J. Neurosci., March 11, 2009; 29(10): 3288 - 3301. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Huang, A. Yamamoto, M. A. Hossain, L. Younes, and S. Mori Quantitative Cortical Mapping of Fractional Anisotropy in Developing Rat Brains J. Neurosci., February 6, 2008; 28(6): 1427 - 1433. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. J. Lein, X. Guo, G.-X. Shi, M. Moholt-Siebert, D. Bruun, and D. A. Andres The Novel GTPase Rit Differentially Regulates Axonal and Dendritic Growth J. Neurosci., April 25, 2007; 27(17): 4725 - 4736. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Raven, E. C. T. Oh, A. Swaroop, and B. E. Reese Afferent Control of Horizontal Cell Morphology Revealed by Genetic Respecification of Rods and Cones J. Neurosci., March 28, 2007; 27(13): 3540 - 3547. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Burkhalter, H. Fiumelli, J. D. Erickson, and J.-L. Martin A Critical Role for System A Amino Acid Transport in the Regulation of Dendritic Development by Brain-derived Neurotrophic Factor (BDNF) J. Biol. Chem., February 23, 2007; 282(8): 5152 - 5159. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. M. de Groot, A. J. M. Coenen, A. Verhofstad, F. van Herp, and G. J. M. Martens In Vivo Induction of Glial Cell Proliferation and Axonal Outgrowth and Myelination by Brain-Derived Neurotrophic Factor Mol. Endocrinol., November 1, 2006; 20(11): 2987 - 2998. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. C Maier and M. E Schwab Sprouting, regeneration and circuit formation in the injured spinal cord: factors and activity Phil Trans R Soc B, September 29, 2006; 361(1473): 1611 - 1634. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. L. Sanchez, B. J. Matthews, M. M. Meynard, B. Hu, S. Javed, and S. Cohen-Cory BDNF increases synapse density in dendrites of developing tectal neurons in vivo Development, July 1, 2006; 133(13): 2477 - 2486. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. M. Papadopoulos, S.-Y. Tsai, J. L. Cheatwood, M. R. Bollnow, B. E. Kolb, M. E. Schwab, and G. L. Kartje Dendritic Plasticity in the Adult Rat Following Middle Cerebral Artery Occlusion and Nogo-A Neutralization Cereb Cortex, April 1, 2006; 16(4): 529 - 536. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. W. Hickmott and I. M. Ethell Dendritic Plasticity in the Adult Neocortex Neuroscientist, February 1, 2006; 12(1): 16 - 28. [Abstract] [PDF]
|
|
|
|
|
|
J. Jaworski, S. Spangler, D. P. Seeburg, C. C. Hoogenraad, and M. Sheng Control of Dendritic Arborization by the Phosphoinositide-3'-Kinase-Akt-Mammalian Target of Rapamycin Pathway J. Neurosci., December 7, 2005; 25(49): 11300 - 11312. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. W. Hickmott Changes in Intrinsic Properties of Pyramidal Neurons in Adult Rat S1 During Cortical Reorganization J Neurophysiol, July 1, 2005; 94(1): 501 - 511. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. M. Y. Moresco, S. Donaldson, A. Williamson, and A. J. Koleske Integrin-Mediated Dendrite Branch Maintenance Requires Abelson (Abl) Family Kinases J. Neurosci., June 29, 2005; 25(26): 6105 - 6118. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. F. Evers, S. Schmitt, M. Sibila, and C. Duch Progress in Functional Neuroanatomy: Precise Automatic Geometric Reconstruction of Neuronal Morphology From Confocal Image Stacks J Neurophysiol, April 1, 2005; 93(4): 2331 - 2342. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Duch and T. Mentel Activity Affects Dendritic Shape and Synapse Elimination during Steroid Controlled Dendritic Retraction in Manduca sexta J. Neurosci., November 3, 2004; 24(44): 9826 - 9837. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. B. Jones, H. Y. Lu, and Q. Lu Abl Tyrosine Kinase Promotes Dendrogenesis by Inducing Actin Cytoskeletal Rearrangements in Cooperation with Rho Family Small GTPases in Hippocampal Neurons J. Neurosci., September 29, 2004; 24(39): 8510 - 8521. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S.-H. Shi, D. N. Cox, D. Wang, L. Y. Jan, and Y.-N. Jan From The Cover: Control of dendrite arborization by an Ig family member, dendrite arborization and synapse maturation 1 (Dasm1) PNAS, September 7, 2004; 101(36): 13341 - 13345. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Schumann, J. Hamstra, B. L. Goodlin-Jones, L. J. Lotspeich, H. Kwon, M. H. Buonocore, C. R. Lammers, A. L. Reiss, and D. G. Amaral The Amygdala Is Enlarged in Children But Not Adolescents with Autism; the Hippocampus Is Enlarged at All Ages J. Neurosci., July 14, 2004; 24(28): 6392 - 6401. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Maravall, I. Y.Y. Koh, W. B. Lindquist, and K. Svoboda Experience-dependent Changes in Basal Dendritic Branching of Layer 2/3 Pyramidal Neurons During a Critical Period for Developmental Plasticity in Rat Barrel Cortex Cereb Cortex, June 1, 2004; 14(6): 655 - 664. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Wirth, A. Brun, J. Grabert, S. Patz, and P. Wahle Accelerated dendritic development of rat cortical pyramidal cells and interneurons after biolistic transfection with BDNF and NT4/5 Development, December 1, 2003; 130(23): 5827 - 5838. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Lee, W. Li, K. Xu, B. A. Bogert, K. Su, and F.-B. Gao Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1 Development, November 15, 2003; 130(22): 5543 - 5552. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. K. Scott, J. E. Reuter, and L. Luo Small GTPase Cdc42 Is Required for Multiple Aspects of Dendritic Morphogenesis J. Neurosci., April 15, 2003; 23(8): 3118 - 3123. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Picones, S C. Chung, and J. I Korenbrot Developmental maturation of passive electrical properties in retinal ganglion cells of rainbow trout J. Physiol., April 1, 2003; 548(1): 71 - 83. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Cohen-Cory The Developing Synapse: Construction and Modulation of Synaptic Structures and Circuits Science, October 25, 2002; 298(5594): 770 - 776. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Lom, J. Cogen, A. L. Sanchez, T. Vu, and S. Cohen-Cory Local and Target-Derived Brain-Derived Neurotrophic Factor Exert Opposing Effects on the Dendritic Arborization of Retinal Ganglion Cells In Vivo J. Neurosci., September 1, 2002; 22(17): 7639 - 7649. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Consoulas, L. L. Restifo, and R. B. Levine Dendritic Remodeling and Growth of Motoneurons during Metamorphosis of Drosophila melanogaster J. Neurosci., June 15, 2002; 22(12): 4906 - 4917. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Vetter, A. Roth, and M. Hausser Propagation of Action Potentials in Dendrites Depends on Dendritic Morphology J Neurophysiol, February 1, 2001; 85(2): 926 - 937. [Abstract] [Full Text] [PDF]
|
|