Cerebral Cortex April 2004; 14:474
© Oxford University Press 2004
Corrigendum
Experience-dependent Regulation of the Zincergic Innervation of Visual Cortex in Adult Monkeys by Richard H. Dyck, Avi Chaudhuri and Max S. Cynader. Cerebral Cortex October 2004, Volume 13 Number 10, pp. 1094–1109Regrettably, several errors occurred in the above paper. The legends to Figures 9 and 10 were incorrect, together with the reference to these figures, mentioned in the third sentence of the last paragraph of the Results section. The complete corrected legends and relevant paragraph are printed below:
Figure 9. Staining for zinc within eye-specific compartments in layer 3 at higher magnification, 24 h after monocular impulse blockade by TTX. The specific cytological compartments responsible for differential levels of staining corresponding to injected versus uninjected eye zones are not readily apparent. A 25–30% increase in the density of zinc staining in deprived eye stripes appears to correspond to a general increase of staining in the neuropil; seen at higher magnification in B (deprived eye zone) compared with C (non-deprived-eye zone). Calibration in A is 500 µm, for B and C are 50 µm.
Figure 10. Staining for zinc in layer 4c
at high magnification, 3 months after enucleation. The cytological compartments responsible for decreased levels of staining in enucleated versus intact eye zones (A; black arrows indicate intact eye stripes, white arrow indicates an enucleated eye stripe), appear, at higher magnification (B, C) to correspond to a general reduction of staining within a reticulated network of pericellular aggregates, in regions previously innervated by the enucleated eye (C). Calibration in A is 300 µm, for B and C are 100 µm.
Paragraph containing text reference to Figures 9 and 10:
In order to determine whether the modified zinc staining levels could be attributed to changes within specific cytological compartments with long- or short-term deprivation, we compared zinc staining within deprived and nondeprived compartments in all layers. Regardless of deprivation method and duration we could not discern the cytological correlate of altered zinc staining by light microscopy. Differences in zinc staining within deprived and nondeprived compartments of layer 3, at 24 h after TTX, are shown in Figure 9, while similar compartments in layer 4c from a 3 month enucleated animal are illustrated in Figure 10 at higher magnification. Modulations of zinc staining levels in all cases were reflected in relative changes in the density of zinc-stained puncta both in layer 3 (Fig. 9 vs 9B) and layer 4c (Fig. 10B vs 10C). Further characterization of the specific cytological locus of change would require ultra-structural analysis by electron microscopy.
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