| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cerebral Cortex, Vol. 10, No. 10, 925-926,
October 2000
© 2000 Oxford University Press
Dendritic Mechanisms in Brain Function and Developmental Disabilities
National Center for Medical Rehabilitation Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
 |
Introduction |
|---|
The papers assembled in this special issue of Cerebral Cortex are part of a continuing dialogue on cellular and molecular aspects of synaptic development and their impact on brain function, which was stimulated by a meeting sponsored by the National Institute of Child Health and Human Development (April 30– May 1, 1998 at the NIH). In recent years, various types of dendritic abnormalities have been described in Down syndrome, fragile-X syndrome, Rett syndrome, autism and other neurodevelopmental disorders. Subtle alterations in dendritic structure or number are precisely the types of abnormalities that would account for a brain that is largely functional, but has subtle deficits in particular cognitive and/or behavioral domains. Remarkable technical advances allow us to focus on the key cellular
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  M. Dierssen, Y. Herault, and X. Estivill Aneuploidy: From a Physiological Mechanism of Variance to Down Syndrome Physiol Rev, July 1, 2009; 89(3): 887 - 920. [Abstract] [Full Text] [PDF]
|
|