Cerebral Cortex, Vol 8, 227-236, Copyright © 1998 by Oxford University Press
N Jain, KC Catania and JH Kaas
An isomorph of the glabrous hand is visible in primary somato-sensory
cortex (area 3b) of owl monkeys in brain sections cut parallel to the
surface and stained for myelin. A mediolateral row of five ovals, separated
by myelin-light septa, represents digits and corresponds precisely with
cortical sites activated by light touch on individual digits in
microelectrode recordings. A number of caudal ovals relate to pads of the
palm. A more distinct septum separates the hand from the more lateral face
representation. Within the face representation, two large myelin-dense
ovals can be identified that are activated by the upper or lower face in a
caudo-rostral sequence. Accidental finger loss or dorsal column section,
deafferentations that result in reorganization of the physiological map in
area 3b, do not alter the morphological map. The proportions for each digit
and palm in the morphological map do not vary across normal and
deafferented animals. Similar isomorphs were also seen in area 3b of
squirrel and macaque monkeys. We conclude that the anatomical isomorph for
the body surface representation in area 3b is a reliable reflection of
normal cortical organization and may be a common feature of the primate
area 3b. The isomorph can provide a reference in studies of somatotopic
reorganization.
ARTICLES
A histologically visible representation of the fingers and palm in primate area 3b and its immutability following long-term deafferentations
Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA. neeraj.jain@vanderbilt.edu
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