Skip Navigation


Cerebral Cortex Advance Access originally published online on March 25, 2009
Cerebral Cortex 2009 19(11):2736-2745; doi:10.1093/cercor/bhp049
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrowOA All Versions of this Article:
19/11/2736    most recent
bhp049v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Google Scholar
Right arrow Articles by Majdandzic, J.
Right arrow Articles by Toni, I.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Majdandzic, J.
Right arrow Articles by Toni, I.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2009 The Authors
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Movement-Specific Repetition Suppression in Ventral and Dorsal Premotor Cortex during Action Observation

Jasminka Majdandzic1,2, Harold Bekkering1,2, Hein T. van Schie3 and Ivan Toni1,2

1 Donders Institute for Brain, Cognition and Behavior, Center for Cognitive Neuroimaging, 2 Donders Institute for Brain, Cognition and Behavior, Center for Cognition, 3 Behavioral Science Institute, Radboud University Nijmegen, 6500 HB Nijmegen, the Netherlands

Address correspondence to email: j.majdandzic{at}donders.ru.nl.

There are several models of premotor cortex contributions to sensorimotor behavior. For instance, the ventral premotor cortex (PMv) appears to be involved in processing visuospatial object properties for grasping, whereas the dorsal premotor cortex (PMd) is involved in using arbitrary rules to guide advance motor planning. These models have focused on individual movements. Here, we examine the premotor responses evoked during the processing of individual movements functionally embedded in an action. We tested whether processing hand–object interactions and action end states would differentially engage PMv and PMd. We used a repetition suppression (RS)–functional magnetic resonance imaging paradigm in which we independently manipulated the observed grip, the end position of the object (independent of its spatial location), and the hand trajectory. By comparing novel and repeated trials for each of these action components, we could isolate RS effects specific to each of them. Repeating the grasp component attenuated activity in right PMv, whereas repeating the end state of the action reduced blood oxygen level–dependent activity in the left PMd. These results suggest that PMv is involved in controlling the kinematic means of an appropriate hand–object interaction, whereas PMd is focused on specifying the desired end state of an action.

Key Words: action observation • PMd • PMv • premotor cortex • repetition suppression


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Neurosci.Home page
E. R. Buch, R. B. Mars, E. D. Boorman, and M. F. S. Rushworth
A Network Centered on Ventral Premotor Cortex Exerts Both Facilitatory and Inhibitory Control over Primary Motor Cortex during Action Reprogramming
J. Neurosci., January 27, 2010; 30(4): 1395 - 1401.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.