Skip Navigation


Cerebral Cortex Advance Access originally published online on September 24, 2007
Cerebral Cortex 2008 18(6):1350-1360; doi:10.1093/cercor/bhm166
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
18/6/1350    most recent
bhm166v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Altmann, C. F.
Right arrow Articles by Kakigi, R.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Altmann, C. F.
Right arrow Articles by Kakigi, R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2007. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Temporal Dynamics of Adaptation to Natural Sounds in the Human Auditory Cortex

Christian F. Altmann1,2, Hiroki Nakata1, Yasuki Noguchi1,3, Koji Inui1, Minoru Hoshiyama1,3, Yoshiki Kaneoke1 and Ryusuke Kakigi1

1 Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444-8585, Japan, 2 Institute of Medical Psychology, Johann-Wolfgang-Goethe University, 60528 Frankfurt am Main, Germany, 3 Department of Health Sciences, Faculty of Medicine, Nagoya University, Higashi-ku, Nagoya 461-8673, Japan

Address correspondence to Christian F. Altmann, Institute of Medical Psychology, Heinrich-Hoffmann-Strasse 10, 60528 Frankfurt am Main, Germany. Email: C.Altmann{at}med.uni-frankfurt.de.

We aimed at testing the cortical representation of complex natural sounds within auditory cortex by conducting 2 human magnetoencephalography experiments. To this end, we employed an adaptation paradigm and presented subjects with pairs of complex stimuli, namely, animal vocalizations and spectrally matched noise. In Experiment 1, we presented stimulus pairs of same or different animal vocalizations and same or different noise. Our results suggest a 2-step process of adaptation effects: first, we observed a general item-unspecific reduction of the N1m peak amplitude at 100 ms, followed by an item-specific amplitude reduction of the P2m component at 200 ms after stimulus onset for both animal vocalizations and noise. Multiple dipole source modeling revealed the right lateral Heschl's gyrus and the bilateral superior temporal gyrus as sites of adaptation. In Experiment 2, we tested for cross-adaptation between animal vocalizations and spectrally matched noise sounds, by presenting pairs of an animal vocalization and its corresponding or a different noise sound. We observed cross-adaptation effects for the P2m component within bilateral superior temporal gyrus. Thus, our results suggest selectivity of the evoked magnetic field at 200 ms after stimulus onset in nonprimary auditory cortex for the spectral fine structure of complex sounds rather than their temporal dynamics.

Key Words: animal vocalizations • complex sounds • MEG • repetition suppression


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.