Skip Navigation


Cerebral Cortex Advance Access originally published online on May 18, 2005
Cerebral Cortex 2006 16(3):346-354; doi:10.1093/cercor/bhi112
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
16/3/346    most recent
bhi112v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (10)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Luders, E.
Right arrow Articles by Toga, A.W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Luders, E.
Right arrow Articles by Toga, A.W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2005. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oupjournals.org

Parasagittal Asymmetries of the Corpus Callosum

E. Luders1, K.L. Narr1, E. Zaidel2, P.M. Thompson1, L. Jancke3 and A.W. Toga1

1 Laboratory of Neuro Imaging, Department of Neurology, Brain Mapping Division, UCLA School of Medicine, Los Angeles, USA, 2 Department of Psychology, UCLA, Los Angeles, USA and 3 Department of Neuropsychology, University of Zurich, Switzerland

Address correspondence to Dr Arthur W. Toga, Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine. 710 Westwood Plaza, 4238 Reed, Los Angeles, CA 90095-1769, USA. Email: toga{at}loni.ucla.edu.

Significant relationships have been reported between midsagittal areas of the corpus callosum and the degree of interhemispheric transfer, functional lateralization and structural brain asymmetries. No study, however, has examined whether parasagittal callosal asymmetries (i.e. those close to the midline of the brain), which may be of specific functional consequence, are present in the human brain. Thus, we applied magnetic resonance imaging and novel computational surface-based methods to encode hemispheric differences in callosal thickness at a very high resolution. Discrete callosal areas were also compared between the hemispheres. Furthermore, acknowledging the frequently reported sex differences in callosal morphology, parasagittal callosal asymmetries were examined within each gender. Results showed significant rightward asymmetries of callosal thickness predominantly in the anterior body and anterior third of the callosum, suggesting a more diffuse functional organization of callosal projections in the right hemisphere. Asymmetries were increased in men, supporting the assumption of a sexually dimorphic organization of male and female brains that involves hemispheric relations and is reflected in the organization and distribution of callosal fibers.

Key Words: gender • lateralization • hemispheres • morphology • sex


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 BrainHome page
B. Weber, E. Luders, J. Faber, S. Richter, C. M. Quesada, H. Urbach, P. M. Thompson, A. W. Toga, C. E. Elger, and C. Helmstaedter
Distinct regional atrophy in the corpus callosum of patients with temporal lobe epilepsy
Brain, December 1, 2007; 130(12): 3149 - 3154.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.