Cerebral Cortex Advance Access originally published online on May 27, 2004
Cerebral Cortex 2004 14(11):1214-1225; doi:10.1093/cercor/bhh082
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
© Oxford University Press 2004
Article |
Remembering Our Past: Functional Neuroanatomy of Recollection of Recent and Very Remote Personal Events
1 Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst St., Toronto, Ontario, Canada M6A 2E1, 2 Department of Psychology, University of Toronto, 100 St-George St., Toronto, Ontario, Canada M5S 3G3
Functional magnetic resonance imaging was used to study brain regions implicated in retrieval of memories that are decades old. To probe autobiographical memory, family photographs were selected by confederates without the participant’s involvement, thereby eliminating many of the variables that potentially confounded previous neuroimaging studies. We found that context-rich memories were associated with activity in lingual and precuneus gyri independently of their age. By contrast, retrosplenial cortex was more active for recent events regardless of memory vividness. Hippocampal activation was related to the richness of re-experiencing (vividness) rather than the age of the memory per se. Remote memories were associated with distributed activation along the rostrocaudal axis of the hippocampus whereas activation associated with recent memories was clustered in the anterior portion. This may explain why circumscribed lesions to the hippocampus disproportionately affect recent memories. These findings are incompatible with theories of long-term memory consolidation, and are more easily accommodated by multiple-trace theory, which posits that detailed memories are always dependent on the hippocampus.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  K. Schon, Y. T. Quiroz, M. E. Hasselmo, and C. E. Stern Greater Working Memory Load Results in Greater Medial Temporal Activity at Retrieval Cereb Cortex, November 1, 2009; 19(11): 2561 - 2571. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Janata The Neural Architecture of Music-Evoked Autobiographical Memories Cereb Cortex, November 1, 2009; 19(11): 2579 - 2594. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Takashima, I. L.C. Nieuwenhuis, O. Jensen, L. M. Talamini, M. Rijpkema, and G. Fernandez Shift from Hippocampal to Neocortical Centered Retrieval Network with Consolidation J. Neurosci., August 12, 2009; 29(32): 10087 - 10093. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. K. Szpunar, J. C. K. Chan, and K. B. McDermott Contextual Processing in Episodic Future Thought Cereb Cortex, July 1, 2009; 19(7): 1539 - 1548. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Hassabis and E. A. Maguire The construction system of the brain Phil Trans R Soc B, May 12, 2009; 364(1521): 1263 - 1271. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Lehn, H.-A. Steffenach, N. M. van Strien, D. J. Veltman, M. P. Witter, and A. K. Haberg A Specific Role of the Human Hippocampus in Recall of Temporal Sequences J. Neurosci., March 18, 2009; 29(11): 3475 - 3484. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Svoboda and B. Levine The Effects of Rehearsal on the Functional Neuroanatomy of Episodic Autobiographical and Semantic Remembering: A Functional Magnetic Resonance Imaging Study J. Neurosci., March 11, 2009; 29(10): 3073 - 3082. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Mendelsohn, O. Furman, I. Navon, and Y. Dudai Subjective vs. documented reality: A case study of long-term real-life autobiographical memory Learn. Mem., January 29, 2009; 16(2): 142 - 146. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. N. Smith and L. R. Squire Medial Temporal Lobe Activity during Retrieval of Semantic Memory Is Related to the Age of the Memory J. Neurosci., January 28, 2009; 29(4): 930 - 938. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Daselaar, H. J. Rice, D. L. Greenberg, R. Cabeza, K. S. LaBar, and D. C. Rubin The Spatiotemporal Dynamics of Autobiographical Memory: Neural Correlates of Recall, Emotional Intensity, and Reliving Cereb Cortex, January 1, 2008; 18(1): 217 - 229. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. E. Berryhill, L. Phuong, L. Picasso, R. Cabeza, and I. R. Olson Parietal Lobe and Episodic Memory: Bilateral Damage Causes Impaired Free Recall of Autobiographical Memory J. Neurosci., December 26, 2007; 27(52): 14415 - 14423. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Noulhiane, P. Piolino, D. Hasboun, S. Clemenceau, M. Baulac, and S. Samson Autobiographical memory after temporal lobe resection: neuropsychological and MRI volumetric findings Brain, December 1, 2007; 130(12): 3184 - 3199. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Viard, P. Piolino, B. Desgranges, G. Chetelat, K. Lebreton, B. Landeau, A. Young, V. De La Sayette, and F. Eustache Hippocampal Activation for Autobiographical Memories over the Entire Lifetime in Healthy Aged Subjects: An fMRI Study Cereb Cortex, October 1, 2007; 17(10): 2453 - 2467. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. R. Addis, M. Moscovitch, and M. P. McAndrews Consequences of hippocampal damage across the autobiographical memory network in left temporal lobe epilepsy Brain, September 1, 2007; 130(9): 2327 - 2342. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Hassabis, D. Kumaran, S. D. Vann, and E. A. Maguire Patients with hippocampal amnesia cannot imagine new experiences PNAS, January 30, 2007; 104(5): 1726 - 1731. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Bright, J. Buckman, A. Fradera, H. Yoshimasu, A. C.F. Colchester, and M. D. Kopelman Retrograde amnesia in patients with hippocampal, medial temporal, temporal lobe, or frontal pathology. Learn. Mem., September 1, 2006; 13(5): 545 - 557. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. S. R. Davidson, D. Anaki, J. A. Saint-Cyr, T. W. Chow, and M. Moscovitch Exploring the recognition memory deficit in Parkinson's disease: estimates of recollection versus familiarity Brain, July 1, 2006; 129(7): 1768 - 1779. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Cavanna and M. R. Trimble The precuneus: a review of its functional anatomy and behavioural correlates Brain, March 1, 2006; 129(3): 564 - 583. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Abe, M. Suzuki, T. Tsukiura, E. Mori, K. Yamaguchi, M. Itoh, and T. Fujii Dissociable Roles of Prefrontal and Anterior Cingulate Cortices in Deception Cereb Cortex, February 1, 2006; 16(2): 192 - 199. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Takashima, K. M. Petersson, F. Rutters, I. Tendolkar, O. Jensen, M. J. Zwarts, B. L. McNaughton, and G. Fernandez From the Cover: Declarative memory consolidation in humans: A prospective functional magnetic resonance imaging study PNAS, January 17, 2006; 103(3): 756 - 761. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Dolcos, K. S. LaBar, and R. Cabeza Remembering one year later: Role of the amygdala and the medial temporal lobe memory system in retrieving emotional memories PNAS, February 15, 2005; 102(7): 2626 - 2631. [Abstract] [Full Text] [PDF]
|
|