Cerebral Cortex, Vol. 13, No. 1, 53-62,
January 2003
© 2003 Oxford University Press
Closed-loop Neuronal Computations: Focus on Vibrissa Somatosensation in Rat
1 Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel, , 2 Department of Physics and , 3 Graduate Program in Neurosciences, University of California at San Diego, La Jolla, CA 92093 and , 4 Institute for Theoretical Physics, University of California at Santa Barbara, Santa Barbara, CA 93106, USA
Address correspondence to Ehud Ahissar, Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel, email: ehud.ahissar{at}weizmann.ac.il, or to David Kleinfeld, email: dk{at}physics.ucsd.edu.
Two classes of neuronal architectures dominate in the ongoing debate on the nature of computing by nervous systems. The first is a predominantly feedforward architecture, in which local interactions among neurons within each processing stage play a less influential role compared with the drive of the input to that stage. The second class is a recurrent network architecture, in which the local interactions among neighboring neurons dominate the dynamics of neuronal activity so that the input acts only to bias or seed the state of the network. The study of sensorimotor networks, however, serves to highlight a third class of architectures, which is neither feedforward nor locally recurrent and where computations depend on large-scale feedback loops. Findings that have emerged from our laboratories and those of our colleagues suggest that the vibrissa sensorimotor system is involved in such closed-loop computations. In particular, single unit responses from vibrissa sensory and motor areas show generic signatures of phase-sensitive detection and control at the level of thalamocortical and corticocortical loops. These loops are likely to be components within a greater closed-loop vibrissa sensorimotor system, which optimizes sensory processing.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  F. Darvas, K. J. Miller, R. P. N. Rao, and J. G. Ojemann Nonlinear Phase-Phase Cross-Frequency Coupling Mediates Communication between Distant Sites in Human Neocortex J. Neurosci., January 14, 2009; 29(2): 426 - 435. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Lottem and R. Azouz Dynamic Translation of Surface Coarseness Into Whisker Vibrations J Neurophysiol, November 1, 2008; 100(5): 2852 - 2865. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Masri, T. Bezdudnaya, J. C. Trageser, and A. Keller Encoding of Stimulus Frequency and Sensor Motion in the Posterior Medial Thalamic Nucleus J Neurophysiol, August 1, 2008; 100(2): 681 - 689. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Chakrabarti, M. Zhang, and K. D. Alloway MI Neuronal Responses to Peripheral Whisker Stimulation: Relationship to Neuronal Activity in SI Barrels and Septa J Neurophysiol, July 1, 2008; 100(1): 50 - 63. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Simony, I. Saraf-Sinik, D. Golomb, and E. Ahissar Sensation-Targeted Motor Control: Every Spike Counts? Focus on: "Whisker Movements Evoked by Stimulation of Single Motor Neurons in the Facial Nucleus of the Rat" J Neurophysiol, June 1, 2008; 99(6): 2757 - 2759. [Full Text] [PDF]
|
|
|
|
|
|
T. A. S. Ewert, C. Vahle-Hinz, and A. K. Engel High-Frequency Whisker Vibration Is Encoded by Phase-Locked Responses of Neurons in the Rat's Barrel Cortex J. Neurosci., May 14, 2008; 28(20): 5359 - 5368. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Li and F. F. Ebner Cortical Modulation of Spatial and Angular Tuning Maps in the Rat Thalamus J. Neurosci., January 3, 2007; 27(1): 167 - 179. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Hipp, E. Arabzadeh, E. Zorzin, J. Conradt, C. Kayser, M. E. Diamond, and P. Konig Texture Signals in Whisker Vibrations J Neurophysiol, March 1, 2006; 95(3): 1792 - 1799. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Golomb, E. Ahissar, and D. Kleinfeld Coding of Stimulus Frequency by Latency in Thalamic Networks Through the Interplay of GABAB-Mediated Feedback and Stimulus Shape J Neurophysiol, March 1, 2006; 95(3): 1735 - 1750. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Kepecs, N. Uchida, and Z. F. Mainen The Sniff as a Unit of Olfactory Processing Chem Senses, February 1, 2006; 31(2): 167 - 179. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. M. Knutsen, D. Derdikman, and E. Ahissar Tracking Whisker and Head Movements in Unrestrained Behaving Rodents J Neurophysiol, April 1, 2005; 93(4): 2294 - 2301. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Feldmeyer, A. Roth, and B. Sakmann Monosynaptic Connections between Pairs of Spiny Stellate Cells in Layer 4 and Pyramidal Cells in Layer 5A Indicate That Lemniscal and Paralemniscal Afferent Pathways Converge in the Infragranular Somatosensory Cortex J. Neurosci., March 30, 2005; 25(13): 3423 - 3431. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. F. Ahrens and D. Kleinfeld Current Flow in Vibrissa Motor Cortex Can Phase-Lock With Exploratory Rhythmic Whisking in Rat J Neurophysiol, September 1, 2004; 92(3): 1700 - 1707. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Ganguly and D. Kleinfeld Goal-directed whisking increases phase-locking between vibrissa movement and electrical activity in primary sensory cortex in rat PNAS, August 17, 2004; 101(33): 12348 - 12353. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. I. Moore Frequency-Dependent Processing in the Vibrissa Sensory System J Neurophysiol, June 1, 2004; 91(6): 2390 - 2399. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. W. Berg and D. Kleinfeld Vibrissa Movement Elicited by Rhythmic Electrical Microstimulation to Motor Cortex in the Aroused Rat Mimics Exploratory Whisking J Neurophysiol, November 1, 2003; 90(5): 2950 - 2963. [Abstract] [Full Text] [PDF]
|
|