Cerebral Cortex, Vol. 10, No. 12, 1176-1184,
December 2000
© 2000 Oxford University Press
Task-specific Repetition Priming in Left Inferior Prefrontal Cortex
1 Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, , 2 Massachusetts General Hospital—Nuclear Magnetic Resonance Center, , 3 Department of Psychology, Harvard University, , 4 Department of Psychology, Washington University, USA
Previous neuroimaging studies have shown that activation in left inferior prefrontal cortices (LIPC) is reduced during repeated (primed) relative to initial (unprimed) stimulus processing. These reductions in anterior (~BA 45/47) and posterior (~BA 44/6) LIPC activation have been interpreted as reflecting implicit memory for initial semantic or phonological processing. However, prior studies do not unambiguously indicate that LIPC priming effects are specific to the recapitulation of higher-level (semantic and/or phonological), rather than lower-level (perceptual), processes. Moreover, no prior study has shown that the patterns of priming in anterior and posterior LIPC regions are dissociable. To address these issues, the present fMRI study examined the nature of priming in LIPC by examining the task-specificity of these effects. Participants initially processed words in either a semantic or a nonsemantic manner. Subsequently, participants were scanned while they made semantic decisions about words that had been previously processed in a semantic manner (within-task repetition), words that had been previously processed in a nonsemantic manner (across-task repetition), and words that had not been previously processed (novel words). Behaviorally, task-specific priming was observed: reaction times to make the semantic decision declined following prior semantic processing but not following prior nonsemantic processing of a word. Priming in anterior LIPC paralleled these results with signal reductions being observed following within-task, but not following across-task, repetition. Importantly, neural priming in posterior LIPC demonstrated a different pattern: priming was observed following both within-task and across-task repetition, with the magnitude of priming tending to be greater in the within-task condition. Direct comparison between anterior and posterior LIPC regions revealed a significant interaction. These findings indicate that anterior and posterior LIPC demonstrate distinct patterns of priming, with priming in the anterior region being task-specific, suggesting that this facilitation derives from repeated semantic processing of a stimulus.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  A. Soldan, Y. Gazes, H. J. Hilton, and Y. Stern Aging Does Not Affect Brain Patterns of Repetition Effects Associated with Perceptual Priming of Novel Objects J. Cogn. Neurosci., October 1, 2008; 20(10): 1762 - 1776. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. Voss, P. J. Reber, M.-M. Mesulam, T. B. Parrish, and K. A. Paller Familiarity and Conceptual Priming Engage Distinct Cortical Networks Cereb Cortex, July 1, 2008; 18(7): 1712 - 1719. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. Hasson, H. C. Nusbaum, and S. L. Small Brain Networks Subserving the Extraction of Sentence Information and Its Encoding to Memory Cereb Cortex, December 1, 2007; 17(12): 2899 - 2913. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Xue and R. A. Poldrack The neural substrates of visual perceptual learning of words: implications for the visual word form area hypothesis. J. Cogn. Neurosci., October 1, 2007; 19(10): 1643 - 1655. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R.E. Hagenbeek, S.A.R.B. Rombouts, D.J. Veltman, J.W. Van Strien, M.P. Witter, P. Scheltens, and F. Barkhof Nonlinear Changes in Brain Activity During Continuous Word Repetition: An Event-Related Multiparametric Functional MR Imaging Study AJNR Am. J. Neuroradiol., October 1, 2007; 28(9): 1715 - 1721. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Rau, G. Fesl, P. Bruhns, P. Havel, B. Braun, J.-C. Tonn, and J. Ilmberger Reproducibility of Activations in Broca Area with Two Language Tasks: A Functional MR Imaging Study AJNR Am. J. Neuroradiol., August 1, 2007; 28(7): 1346 - 1353. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Kristjansson, P. Vuilleumier, S. Schwartz, E. Macaluso, and J. Driver Neural Basis for Priming of Pop-Out during Visual Search Revealed with fMRI Cereb Cortex, July 1, 2007; 17(7): 1612 - 1624. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. T. Wehner, S. P. Ahlfors, and M. Mody The Influence of Semantic Processing on Phonological Decisions in Children and Adults: A Magnetoencephalography (MEG) Study J Speech Lang Hear Res, June 1, 2007; 50(3): 716 - 731. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Ryan and D. Schnyer Regional Specificity of Format-Specific Priming Effects in Mirror Word Reading Using Functional Magnetic Resonance Imaging Cereb Cortex, April 1, 2007; 17(4): 982 - 992. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. R. Kuperberg, T. Deckersbach, D. J. Holt, D. Goff, and W. C. West Increased Temporal and Prefrontal Activity in Response to Semantic Associations in Schizophrenia Arch Gen Psychiatry, February 1, 2007; 64(2): 138 - 151. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. Hasson, H. C. Nusbaum, and S. L. Small Repetition Suppression for Spoken Sentences and the Effect of Task Demands J. Cogn. Neurosci., December 1, 2006; 18(12): 2013 - 2029. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Orfanidou, W. D. Marslen-Wilson, and M. H. Davis Neural response suppression predicts repetition priming of spoken words and pseudowords. J. Cogn. Neurosci., August 1, 2006; 18(8): 1237 - 1252. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. T. Gold, D. A. Balota, S. J. Jones, D. K. Powell, C. D. Smith, and A. H. Andersen Dissociation of automatic and strategic lexical-semantics: functional magnetic resonance imaging evidence for differing roles of multiple frontotemporal regions. J. Neurosci., June 14, 2006; 26(24): 6523 - 6532. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Lind, J. Persson, M. Ingvar, A. Larsson, M. Cruts, C. Van Broeckhoven, R. Adolfsson, L. Backman, L.-G. Nilsson, K. M. Petersson, et al. Reduced functional brain activity response in cognitively intact apolipoprotein E {varepsilon}4 carriers Brain, May 1, 2006; 129(5): 1240 - 1248. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Sakai and R. E. Passingham Prefrontal Set Activity Predicts Rule-Specific Neural Processing during Subsequent Cognitive Performance J. Neurosci., January 25, 2006; 26(4): 1211 - 1218. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. S. Blumenfeld and C. Ranganath Dorsolateral Prefrontal Cortex Promotes Long-Term Memory Formation through Its Role in Working Memory Organization J. Neurosci., January 18, 2006; 26(3): 916 - 925. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. Voss and K. A. Paller Fluent Conceptual Processing and Explicit Memory for Faces Are Electrophysiologically Distinct J. Neurosci., January 18, 2006; 26(3): 926 - 933. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Badre and A. D. Wagner Frontal Lobe Mechanisms that Resolve Proactive Interference Cereb Cortex, December 1, 2005; 15(12): 2003 - 2012. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Zago, M. J. Fenske, E. Aminoff, and M. Bar The Rise and Fall of Priming: How Visual Exposure Shapes Cortical Representations of Objects Cereb Cortex, November 1, 2005; 15(11): 1655 - 1665. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. G. Dobbins and A. D. Wagner Domain-general and Domain-sensitive Prefrontal Mechanisms for Recollecting Events and Detecting Novelty Cereb Cortex, November 1, 2005; 15(11): 1768 - 1778. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. T. Gold, D. A. Balota, B. A. Kirchhoff, and R. L. Buckner Common and Dissociable Activation Patterns Associated with Controlled Semantic and Phonological Processing: Evidence from fMRI Adaptation Cereb Cortex, September 1, 2005; 15(9): 1438 - 1450. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Winhuisen, A. Thiel, B. Schumacher, J. Kessler, J. Rudolf, W. F. Haupt, and W. D. Heiss Role of the Contralateral Inferior Frontal Gyrus in Recovery of Language Function in Poststroke Aphasia: A Combined Repetitive Transcranial Magnetic Stimulation and Positron Emission Tomography Study Stroke, August 1, 2005; 36(8): 1759 - 1763. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. N. A. Henson, M. Hornberger, and M. D. Rugg Further Dissociating the Processes Involved in Recognition Memory: An fMRI Study J. Cogn. Neurosci., July 1, 2005; 17(7): 1058 - 1073. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. Kahn, A. Pascual-Leone, H. Theoret, F. Fregni, D. Clark, and A. D. Wagner Transient Disruption of Ventrolateral Prefrontal Cortex During Verbal Encoding Affects Subsequent Memory Performance J Neurophysiol, July 1, 2005; 94(1): 688 - 698. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Strangman, W. C. Heindel, J. A. Anderson, and J. P. Sutton Learning Motor Sequences with and without Knowledge of Governing Rules Neurorehabil Neural Repair, June 1, 2005; 19(2): 93 - 114. [Abstract] [PDF]
|
|
|
|
|
|
C. J. Fiebach, T. Gruber, and G. G. Supp Neuronal Mechanisms of Repetition Priming in Occipitotemporal Cortex: Spatiotemporal Evidence from Functional Magnetic Resonance Imaging and Electroencephalography J. Neurosci., March 30, 2005; 25(13): 3414 - 3422. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. R. Cardillo, J. Aydelott, P. M. Matthews, and J. T. Devlin Left Inferior Prefrontal Cortex Activity Reflects Inhibitory Rather Than Facilitatory Priming J. Cogn. Neurosci., November 1, 2004; 16(9): 1552 - 1561. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Maccotta and R. L. Buckner Evidence for Neural Effects of Repetition that Directly Correlate with Behavioral Priming J. Cogn. Neurosci., November 1, 2004; 16(9): 1625 - 1632. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Noguchi, K. Inui, and R. Kakigi Temporal Dynamics of Neural Adaptation Effect in the Human Visual Ventral Stream J. Neurosci., July 14, 2004; 24(28): 6283 - 6290. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Bergerbest, D. G. Ghahremani, and J. D.E. Gabrieli Neural Correlates of Auditory Repetition Priming: Reduced fMRI Activation in the Auditory Cortex J. Cogn. Neurosci., July 1, 2004; 16(6): 966 - 977. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. Noppeney and C. J. Price An fMRI Study of Syntactic Adaptation J. Cogn. Neurosci., May 1, 2004; 16(4): 702 - 713. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Giesbrecht, C. C. Camblin, and T. Y. Swaab Separable Effects of Semantic Priming and Imageability on Word Processing in Human Cortex Cereb Cortex, May 1, 2004; 14(5): 521 - 529. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Rissman, J. C. Eliassen, and S. E. Blumstein An Event-Related fMRI Investigation of Implicit Semantic Priming J. Cogn. Neurosci., November 1, 2003; 15(8): 1160 - 1175. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Velanova, L. L. Jacoby, M. E. Wheeler, M. P. McAvoy, S. E. Petersen, and R. L. Buckner Functional-Anatomic Correlates of Sustained and Transient Processing Components Engaged during Controlled Retrieval J. Neurosci., September 17, 2003; 23(24): 8460 - 8470. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. van Turennout, L. Bielamowicz, and A. Martin Modulation of Neural Activity during Object Naming: Effects of Time and Practice Cereb Cortex, April 1, 2003; 13(4): 381 - 391. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Badre and A. D. Wagner Semantic retrieval, mnemonic control, and prefrontal cortex. Behav Cogn Neurosci Rev, September 1, 2002; 1(3): 206 - 218. [Abstract] [PDF]
|
|
|
|
|
|
L. L. Chao, J. Weisberg, and A. Martin Experience-dependent Modulation of Category-related Cortical Activity Cereb Cortex, May 1, 2002; 12(5): 545 - 551. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Davachi, A. Maril, and A. D. Wagner When Keeping in Mind Supports Later Bringing to Mind: Neural Markers of Phonological Rehearsal Predict Subsequent Remembering J. Cogn. Neurosci., November 1, 2001; 13(8): 1059 - 1070. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Thiel, R. N. A. Henson, J. S. Morris, K. J. Friston, and R. J. Dolan Pharmacological Modulation of Behavioral and Neuronal Correlates of Repetition Priming J. Neurosci., September 1, 2001; 21(17): 6846 - 6852. [Abstract] [Full Text] [PDF]
|
|