Cerebral Cortex, Vol. 10, No. 11, 1053-1065,
November 2000
© 2000 Oxford University Press
The Multiple Roles of Visual Cortical Areas MT/MST in Remembering the Direction of Visual Motion
Department of Neurobiology & Anatomy and Center for Visual Science, University of Rochester, Rochester, NY 14642, USA
Although the role of cortical areas MT and MST (MT/MST) in the processing of directional motion information is well established, little is known about the way these areas contribute to the execution of complex behavioral tasks requiring the use of such information. We tested monkeys with unilateral lesions of these areas on a visual working memory task in which motion signals not only had to be encoded, but also stored for brief periods of time and then retrieved. The monkeys compared the directions of motion of two random-dot stimuli, sample and test, separated by a temporal delay. By increasing the temporal delay and spatially separating the two stimuli, placing one in the affected visual field and the other in the intact visual field, we were able to assess the contribution of MT/MST to specific components of the task: encoding (sample), retention (delay) and encoding/retrieval/comparison (test). We found that the effects of MT/MST lesions on specific components depended upon the demands of the task and the nature of the visual motion stimuli. Whenever stimuli consisted of random dots moving in a broad range of directions, MT/MST lesions appeared to affect encoding. Furthermore, when the lesions affected encoding of the sample, retention of the direction of stimulus motion was also affected. However, when the stimulus was coherent and the emphasis of the task was on the comparison of small direction differences, the absence of MT/MST had major impact on the retrieval/comparison component of the task and not on encoding or storage.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  W. S. Ong, N. Hooshvar, M. Zhang, and J. W. Bisley Psychophysical Evidence for Spatiotopic Processing in Area MT in a Short-Term Memory for Motion Task J Neurophysiol, October 1, 2009; 102(4): 2435 - 2440. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. J. McKeefry, M. P. Burton, C. Vakrou, B. T. Barrett, and A. B. Morland Induced Deficits in Speed Perception by Transcranial Magnetic Stimulation of Human Cortical Areas V5/MT+ and V3A J. Neurosci., July 2, 2008; 28(27): 6848 - 6857. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Ruiz-Ruiz and J. C. Martinez-Trujillo Human Updating of Visual Motion Direction During Head Rotations J Neurophysiol, May 1, 2008; 99(5): 2558 - 2576. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Zaksas and T. Pasternak Directional Signals in the Prefrontal Cortex and in Area MT during a Working Memory for Visual Motion Task. J. Neurosci., November 8, 2006; 26(45): 11726 - 11742. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Zaksas and T. Pasternak Area MT Neurons Respond to Visual Motion Distant From Their Receptive Fields J Neurophysiol, December 1, 2005; 94(6): 4156 - 4167. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z.-L. Lu, W. Chu, B. A. Dosher, and S. Lee Independent perceptual learning in monocular and binocular motion systems PNAS, April 12, 2005; 102(15): 5624 - 5629. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. R. Huxlin and T. Pasternak Training-induced Recovery of Visual Motion Perception after Extrastriate Cortical Damage in the Adult Cat Cereb Cortex, January 1, 2004; 14(1): 81 - 90. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W. Bisley, D. Zaksas, J. A. Droll, and T. Pasternak Activity of Neurons in Cortical Area MT During a Memory for Motion Task J Neurophysiol, January 1, 2004; 91(1): 286 - 300. [Abstract] [Full Text]
|
|
|
|
|
|
T. Pasternak and D. Zaksas Stimulus Specificity and Temporal Dynamics of Working Memory for Visual Motion J Neurophysiol, October 1, 2003; 90(4): 2757 - 2762. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Campana, A. Cowey, and V. Walsh Priming of Motion Direction and Area V5/MT: a Test of Perceptual Memory Cereb Cortex, June 1, 2002; 12(6): 663 - 669. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Ben-Yehudah, E. Sackett, L. Malchi-Ginzberg, and M. Ahissar Impaired temporal contrast sensitivity in dyslexics is specific to retain-and-compare paradigms Brain, July 1, 2001; 124(7): 1381 - 1395. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W. Bisley, D. Zaksas, and T. Pasternak Microstimulation of Cortical Area MT Affects Performance on a Visual Working Memory Task J Neurophysiol, January 1, 2001; 85(1): 187 - 196. [Abstract] [Full Text] [PDF]
|
|